Tesamorelin (10mg) – Lyophilized Peptide Reagent for Laboratory Research

Tesamorelin (10mg) | Analytical Research Grade

Overview

Tesamorelin is a synthetic 44-amino acid polypeptide and a stabilized analog of Growth Hormone Releasing Hormone (GHRH). It is characterized by an N-terminal modification that increases resistance to enzymatic degradation by dipeptidyl aminopeptidase IV. This compound is a primary subject in molecular biochemistry and endocrine signaling research due to its highly specific receptor affinity.

Biochemical Interactions

In laboratory models, Tesamorelin is utilized to observe the activation of GHRH receptors. Research focuses on the compound’s ability to trigger specific signaling cascades without the rapid degradation seen in endogenous analogs.

Areas of laboratory study include:

• Receptor-ligand binding affinity and kinetics.

• In-vitro GHRH receptor agonist pathways.

• Biochemical regulation of lipid metabolism pathways.

• Molecular signaling in adipose tissue research models.

• Comparative stability of N-terminal modified peptides.

Research Applications

Tesamorelin is currently utilized in various scientific research frameworks, including:

• Endocrine Signaling: Investigating the modulation of the GHRH axis.

• Metabolic Biochemistry: Studies involving lipid-related enzymatic activities.

• Proteomics: Analysis of 44-amino acid peptide stability and synthesis.

• Cellular Homeostasis: Research into regulated growth factor secretion in controlled environments.

Structural Characteristics

• Peptide Type: GHRH Analog / Synthetic Polypeptide

• Sequence Length: 44 Amino Acids

• Molecular Formula: C₂₂₁H₃₆₆N₇₂O₆₇S

• Molecular Weight: 5135.9 g/mol

• Purity: See Certificate of Analysis

• Format: Lyophilized White Powder

Handling and Storage

• Temperature: Store at 2–8°C for immediate use; -20°C for long-term stability.

• Environment: Store in a cool, dry place away from direct light.

• Integrity: Maintain in the original vacuum-sealed vial to prevent moisture contamination.

• Reconstitution: For laboratory analysis, use appropriate sterile buffers (e.g., 0.9% NaCl).

Tesamorelin’s enzymatic-degradation resistance is most often characterised against the unmodified GHRH fragment, making the sermorelin peptide (GHRH 1-29) a standard comparator in these study designs. For laboratory research use only.