Retatrutide (LY3437943) – Triple Agonist Research (5mg – 30mg)

Overview

Retatrutide is a synthetic, long-acting “triple agonist” that targets three distinct hormonal receptors: the glucagon-like pep-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor (GCGR). This unique trifecta of receptor affinity makes Retatrutide a significant focus in biochemical research involving multi-pathway endocrine signaling.

This product is supplied as a lyophilized (freeze-dried) reagent intended strictly for laboratory and scientific research purposes.

Biochemical Characteristics

• Molecular Formula: C221​H342​N54​O68​

• Molecular Weight: Approximately $4731.33$ g/mol

• Purity: ≥ 99% (verified by HPLC & MS analysis)

• Receptor Affinity: Triple Agonist (GLP-1R, GIPR, and GCGR)

• Form: White Lyophilized Powder

Research Applications

Retatrutide is utilized in advanced laboratory research to investigate the synergistic effects of simultaneous receptor activation. Key areas of scientific study include:

• Signal Transduction: Analyzing the intracellular signaling cascades triggered by multi-receptor agonism.

• Metabolic Flux Research: Studying the biochemical impact of glucagon receptor activation in combination with incretin mimetics.

• Endocrine Homeostasis: Observation of the molecule’s role in regulating complex hormone axes in research models.

• Proteomics: Analysis of the stability and metabolic degradation pathways of multi-agonist compounds.

Storage and Laboratory Handling

• Storage: Store at -20°C for long-term stability. The product is stable at room temperature for short-term shipping but should be frozen upon receipt to maintain integrity.

• Light Sensitivity: Keep vials away from direct UV light exposure.

• Reconstitution: For laboratory research, the substance should be reconstituted with an appropriate sterile buffer (0.9% Sodium Chloride or Bacteriostatic Water). Use only within a controlled laboratory setting.

Mandatory Compliance Disclaimer

WARNING: This product is a Research Chemical and is NOT FOR HUMAN CONSUMPTION. It is not a drug, food, or cosmetic. It is not intended for the diagnosis, treatment, cure, or prevention of any medical condition, including obesity or metabolic disorders. This product is intended for In-Vitro Laboratory Research only. Any use of this product in a human or animal therapeutic capacity is strictly prohibited and may result in legal or health consequences.